TERT promoter mutations are associated with distant metastases in upper tract urothelial carcinomas and serve as urinary biomarkers detected by a sensitive castPCR

TERT promoter C228T and C250T mutations occur in various malignancies including bladder cancer (BC) and may serve as urinary tumor markers. However, the mutation association with clinical variables in upper tract urothelial carcinomas (UTUCs) is unclear. There is also a lack of sensitive tools to de...

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Detalles Bibliográficos
Publicado en:Oncotarget
Autores principales: Wang, Kun, Liu, Tiantian, Ge, Nan, Liu, Li, Yuan, Xiaotian, Liu, Jikai, Kong, Feng, Wang, Chang, Ren, Hongbo, Yan, Keqiang, Hu, Sanyuan, Xu, Zhonghua, Björkholm, Magnus, Fan, Yidong, Zhao, Shengtian, Liu, Cheng, Xu, Dawei
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2014
Materias:
Clinical Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4322995/
https://ncbi.nlm.nih.gov/pubmed/25474136
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