TERT promoter mutations are associated with distant metastases in upper tract urothelial carcinomas and serve as urinary biomarkers detected by a sensitive castPCR

TERT promoter C228T and C250T mutations occur in various malignancies including bladder cancer (BC) and may serve as urinary tumor markers. However, the mutation association with clinical variables in upper tract urothelial carcinomas (UTUCs) is unclear. There is also a lack of sensitive tools to de...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Wang, Kun, Liu, Tiantian, Ge, Nan, Liu, Li, Yuan, Xiaotian, Liu, Jikai, Kong, Feng, Wang, Chang, Ren, Hongbo, Yan, Keqiang, Hu, Sanyuan, Xu, Zhonghua, Björkholm, Magnus, Fan, Yidong, Zhao, Shengtian, Liu, Cheng, Xu, Dawei
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Clinical Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4322995/
https://ncbi.nlm.nih.gov/pubmed/25474136
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