Acidosis promotes invasiveness of breast cancer cells through ROS-AKT-NF-κB pathway

It is well known that acidic microenvironment promotes tumorigenesis, however, the underlying mechanism remains largely unknown. In the present study, we show that acidosis promotes invasiveness of breast cancer cells through a series of signaling events. First, our study indicates that NF-κB is a k...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Gupta, Subash C., Singh, Ramesh, Pochampally, Radhika, Watabe, Kounosuke, Mo, Yin-Yuan
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2014
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4322981/
https://ncbi.nlm.nih.gov/pubmed/25504433
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