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Acidosis promotes invasiveness of breast cancer cells through ROS-AKT-NF-κB pathway

It is well known that acidic microenvironment promotes tumorigenesis, however, the underlying mechanism remains largely unknown. In the present study, we show that acidosis promotes invasiveness of breast cancer cells through a series of signaling events. First, our study indicates that NF-κB is a k...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Oncotarget
Main Authors: Gupta, Subash C., Singh, Ramesh, Pochampally, Radhika, Watabe, Kounosuke, Mo, Yin-Yuan
פורמט: Artigo
שפה:Inglês
יצא לאור: Impact Journals LLC 2014
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4322981/
https://ncbi.nlm.nih.gov/pubmed/25504433
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