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Synthesis, Structure-Activity Relationship, and Mechanistic Investigation of Lithocholic Acid Amphiphiles for Colon Cancer Therapy

We report a structure-activity relationship of lithocholic acid amphiphiles for their anticancer activities against colon cancer. We synthesized ten cationic amphiphiles differing in nature of cationic charged head groups using lithocholic acid. We observed that anticancer activities of these amphip...

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Detalles Bibliográficos
Publicado en:Medchemcomm
Main Authors: Singh, Manish, Bansal, Sandhya, Kundu, Somanath, Bhargava, Priyanshu, Singh, Ashima, Motiani, Rajender K., Shyam, Radhey, Sreekanth, Vedagopuram, Sengupta, Sagar, Bajaj, Avinash
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4322782/
https://ncbi.nlm.nih.gov/pubmed/25685308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C4MD00223G
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