Xeroderma pigmentosum cells with normal levels of excision repair have a defect in DNA synthesis after UV-irradiation.

Cells cultured from most patients suffering from the sunlight-sensitive hereditary disorder xeroderma pigmentosum are defective in the ability to excise ultraviolet light (UV)-induced pyrimidine dimers from their DNA. There is, however, one class of these patients whose cells are completely normal i...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Lehman, A R, Kirk-Bell, S, Arlett, C F, Paterson, M C, Lohman, P H, de Weerd-Kastelein, E A, Bootsma, D
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1975
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC432274/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1054497/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.72.1.219
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