Xeroderma pigmentosum cells with normal levels of excision repair have a defect in DNA synthesis after UV-irradiation.

Cells cultured from most patients suffering from the sunlight-sensitive hereditary disorder xeroderma pigmentosum are defective in the ability to excise ultraviolet light (UV)-induced pyrimidine dimers from their DNA. There is, however, one class of these patients whose cells are completely normal i...

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Autors principals: Lehman, A R, Kirk-Bell, S, Arlett, C F, Paterson, M C, Lohman, P H, de Weerd-Kastelein, E A, Bootsma, D
Format: Artigo
Idioma:Inglês
Publicat: 1975
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC432274/
https://ncbi.nlm.nih.gov/pubmed/1054497
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