Deficiency in the Nuclease Activity of Xeroderma Pigmentosum G in Mice Leads to Hypersensitivity to UV Irradiation

Xeroderma pigmentosum (XP) is a human disorder which is characterized by hypersensitivity to sunlight and elevated incidence of skin cancer. The disease is caused by mutations in genes that encode components of the nucleotide excision repair pathway. The gene product of XP complementation group G (X...

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Detalhes bibliográficos
Main Authors: Tian, Ming, Jones, David A., Smith, Michele, Shinkura, Reiko, Alt, Frederick W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC355871/
https://ncbi.nlm.nih.gov/pubmed/14993263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.6.2237-2242.2004
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