The Effect of Hyperglycaemia on In Vitro Cytokine Production and Macrophage Infection with Mycobacterium tuberculosis

Type 2 diabetes mellitus is an established risk factor for tuberculosis but the underlying mechanisms are largely unknown. We examined the effects of hyperglycaemia, a hallmark of diabetes, on the cytokine response to and macrophage infection with Mycobacterium tuberculosis. Increasing in vitro gluc...

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Pubblicato in:PLoS One
Autori principali: Lachmandas, Ekta, Vrieling, Frank, Wilson, Louis G., Joosten, Simone A., Netea, Mihai G., Ottenhoff, Tom H., van Crevel, Reinout
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4322041/
https://ncbi.nlm.nih.gov/pubmed/25664765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0117941
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