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Overexpression of parkin in rat nigrostriatal dopamine system protects against methamphetamine neurotoxicity

Methamphetamine (METH) is a central nervous system psychostimulant with a high potential for abuse. At high doses, METH causes a selective degeneration of dopaminergic terminals in the striatum, sparing other striatal terminals and cell bodies. We previously detected a deficit in parkin after binge...

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Detalhes bibliográficos
Publicado no:Exp Neurol
Main Authors: Liu, Bin, Traini, Roberta, Killinger, Bryan, Schneider, Bernard, Moszczynska, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4321803/
https://ncbi.nlm.nih.gov/pubmed/23313192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2013.01.001
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