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CTLA-4 blockade plus adoptive T cell transfer promotes optimal melanoma immunity in mice

Immunotherapeutic approaches to the treatment of advanced melanoma have relied on strategies that augment the responsiveness of endogenous tumor-specific T cell populations (e.g., CTLA-4 blockade-mediated checkpoint inhibition) or introduce exogenously-prepared tumor-specific T cell populations (e.g...

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Detalhes bibliográficos
Publicado no:J Immunother
Main Authors: Mahvi, David A., Meyers, Justin V., Tatar, Andrew J., Contreras, Amanda, Suresh, M., Leverson, Glen E., Sen, Siddhartha, Cho, Clifford S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4321765/
https://ncbi.nlm.nih.gov/pubmed/25658614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0000000000000064
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