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Structural analysis of human dual-specificity phosphatase 22 complexed with a phosphotyrosine-like substrate

4-Nitrophenyl phosphate (p-nitrophenyl phosphate, pNPP) is widely used as a small molecule phosphotyrosine-like substrate in activity assays for protein tyrosine phosphatases. It is a colorless substrate that upon hydrolysis is converted to a yellow 4-nitrophenolate ion that can be monitored by abso...

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Detalhes bibliográficos
Publicado no:Acta Crystallogr F Struct Biol Commun
Main Authors: Lountos, George T., Cherry, Scott, Tropea, Joseph E., Waugh, David S.
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4321476/
https://ncbi.nlm.nih.gov/pubmed/25664796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X15000217
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