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Crystal structure of the human dual specificity phosphatase 1 catalytic domain
The dual specificity phosphatase DUSP1 was the first mitogen activated protein kinase phosphatase (MKP) to be identified. It dephosphorylates conserved tyrosine and threonine residues in the activation loops of mitogen activated protein kinases ERK2, JNK1 and p38‐alpha. Here, we report the crystal s...
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| Published in: | Protein Sci |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
John Wiley and Sons Inc.
2017
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5775162/ https://ncbi.nlm.nih.gov/pubmed/29052270 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3328 |
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