Three-dimensional structure of an intact human immunoglobulin.

We have examined the low-resolution structure of a complete human IgG1 using known domain coordinates from crystallographic investigations of immunoglobulin fragment structures. Our results indicate that the Fc portion of this molecule has a structure similar to that of an isolated Fc fragment, with...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Silverton, E W, Navia, M A, Davies, D R
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1977
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC432116/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/270751/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.74.11.5140
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