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Three-dimensional structure of an intact human immunoglobulin.

We have examined the low-resolution structure of a complete human IgG1 using known domain coordinates from crystallographic investigations of immunoglobulin fragment structures. Our results indicate that the Fc portion of this molecule has a structure similar to that of an isolated Fc fragment, with...

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Dettagli Bibliografici
Autori principali: Silverton, E W, Navia, M A, Davies, D R
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1977
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC432116/
https://ncbi.nlm.nih.gov/pubmed/270751
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