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A preliminary exploration on DNA methylation of transgene across generations in transgenic rats
Epigenetic heritability is an important issue in the field of genetics and also in the development of many human diseases. In this study, we created a transgenic rat model and investigated the transgenerational methylation patterns in these animals. The transgene DNA fragment was unmethylated before...
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| 出版年: | Sci Rep |
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| 主要な著者: | , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2015
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4321119/ https://ncbi.nlm.nih.gov/pubmed/25659774 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep08292 |
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