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A method to evaluate genome-wide methylation in archival formalin-fixed, paraffin-embedded ovarian epithelial cells.

The use of DNA from archival formalin and paraffin embedded (FFPE) tissue for genetic and epigenetic analyses may be problematic, since the DNA is often degraded and only limited amounts may be available. Thus, it is currently not known whether genome-wide methylation can be reliably assessed in DNA...

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Bibliografische gegevens
Hoofdauteurs: Qiling Li, Min Li, Li Ma, Wenzhi Li, Xuehong Wu, Jendai Richards, Guoxing Fu, Wei Xu, Tameka Bythwood, Xu Li, Jianxin Wang, Qing Song
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science (PLoS) 2014-01-01
Reeks:PLoS ONE
Online toegang:http://europepmc.org/articles/PMC4136734?pdf=render
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