Overdominance Effect of the Bovine Ghrelin Receptor (GHSR1a)-DelR242 Locus on Growth in Japanese Shorthorn Weaner Bulls: Heterozygote Advantage in Bull Selection and Molecular Mechanisms

Ghrelin and the ghrelin receptor (GHSR1a) are involved in growth hormone secretion, food intake, and several other important functions. Ghrelin acts on GHSR1a and induces signal transduction via the Gαq subunit. In our previous study, we identified the DelR242 (3R) allele, a truncated 3-arginine res...

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Detalhes bibliográficos
Publicado no:G3 (Bethesda)
Main Authors: Komatsu, Masanori, Sato, Yoichi, Negami, Tatsuki, Terada, Tohru, Sasaki, Osamu, Yasuda, Jumpei, Arakawa, Aisaku, Yoshida, Chikara, Takahashi, Hideaki, Malau-Aduli, Aduli E. O., Suzuki, Keiichi, Shimizu, Kentaro
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2014
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Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4321035/
https://ncbi.nlm.nih.gov/pubmed/25538099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.114.016105
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