The Effects of Heparins on the Liver: Application of Mechanistic Serum Biomarkers in a Randomized Study in Healthy Volunteers

Heparins have been reported to cause elevations in serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) but have not been associated with clinically significant liver injury. The mechanisms underlying these benign laboratory abnormalities are unknown. Forty-eight healthy men wer...

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Detalhes bibliográficos
Publicado no:Clin Pharmacol Ther
Main Authors: Harrill, A H, Roach, J, Fier, I, Eaddy, J S, Kurtz, C L, Antoine, D J, Spencer, D M, Kishimoto, T K, Pisetsky, D S, Park, B K, Watkins, P B
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2012
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4320779/
https://ncbi.nlm.nih.gov/pubmed/22739141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/clpt.2012.40
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