Chronic myeloid leukemia-derived exosomes promote tumor growth through an autocrine mechanism

BACKGROUND: Chronic myeloid leukemia (CML) is a clonal hematopoietic stem cell disorder in which leukemic cells display a reciprocal t(9:22) chromosomal translocation that results in the formation of the chimeric BCR-ABL oncoprotein, with a constitutive tyrosine kinase activity. Consequently, BCR-AB...

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Detalhes bibliográficos
Publicado no:Cell Commun Signal
Main Authors: Raimondo, Stefania, Saieva, Laura, Corrado, Chiara, Fontana, Simona, Flugy, Anna, Rizzo, Aroldo, De Leo, Giacomo, Alessandro, Riccardo
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4320527/
https://ncbi.nlm.nih.gov/pubmed/25644060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-015-0086-x
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