Carboxyamidotriazole-Orotate Inhibits the Growth of Imatinib-Resistant Chronic Myeloid Leukaemia Cells and Modulates Exosomes-Stimulated Angiogenesis

The Bcr/Abl kinase has been targeted for the treatment of chronic myelogenous leukaemia (CML) by imatinib mesylate. While imatinib has been extremely effective for chronic phase CML, blast crisis CML are often resistant. New therapeutic options are therefore needed for this fatal disease. Although m...

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Main Authors: Corrado, Chiara, Flugy, Anna Maria, Taverna, Simona, Raimondo, Stefania, Guggino, Giuliana, Karmali, Rashida, De Leo, Giacomo, Alessandro, Riccardo
格式: Artigo
語言:Inglês
出版: Public Library of Science 2012
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3411738/
https://ncbi.nlm.nih.gov/pubmed/22879938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0042310
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