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Knockdown of MVK does not lead to changes in NALP3 expression or activation
BACKGROUND: Mutations in the Mevalonate Kinase gene (MVK) are causes of a rare autoinflammatory disease: Mevalonate Kinase Deficiency and its more acute manifestation, Mevalonic Aciduria. The latter is characterized, among other features, by neuroinflammation, developmental delay and ataxia, due to...
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| Publicado no: | J Inflamm (Lond) |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4320511/ https://ncbi.nlm.nih.gov/pubmed/25663823 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12950-015-0048-5 |
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