Single missense mutation in the tyrosine kinase catalytic domain of the RET protooncogene is associated with multiple endocrine neoplasia type 2B.

Multiple endocrine neoplasia type 2B (MEN 2B) is a human cancer syndrome characterized by medullary thyroid carcinoma (MTC), pheochromocytomas, mucosal neuromas, ganglioneuromas of the intestinal tract, and skeletal and ophthalmic abnormalities. It appears both as an inherited disorder and as de nov...

Descripció completa

Dades bibliogràfiques

Publicat a:	Proc Natl Acad Sci U S A
Autors principals:	Carlson, K M, Dou, S, Chi, D, Scavarda, N, Toshima, K, Jackson, C E, Wells, S A, Goodfellow, P J, Donis-Keller, H
Format:	Artigo
Idioma:	Inglês
Publicat:	National Academy of Sciences 1994
Matèries:	Research Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC43203/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7906417/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.4.1579
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!