Somatic Mutations in Exons 10, 11, and 16 of the RET Protooncogene in Medullary Thyroid Carcinoma Patients

Introduction: Medullary thyroid carcinoma (MTC) comprises nearly 5% of all cases of thyroid cancer (TC). Aberrant activation of RET (rearranged during transfection) signaling via somatic mutations is the basic molecular mechanism of MTC tumorigenicity. In this study, we determined the incidence of R...

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Autors principals:	Elham Shakiba, Mehdi Hedayati, Ahmad Majd, Monireh Movahedi
Format:	Artigo
Idioma:	Inglês
Publicat:	Zabol University of Medical sciences 2020-09-01
Col·lecció:	International Journal of Basic Science in Medicine
Matèries:	ret gene somatic mutations iranian patient medullary thyroid carcinoma thyroid caner
Accés en línia:	http://ijbsm.zbmu.ac.ir/PDF/ijbsm-20430
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