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Somatic Mutations in Exons 10, 11, and 16 of the RET Protooncogene in Medullary Thyroid Carcinoma Patients

Introduction: Medullary thyroid carcinoma (MTC) comprises nearly 5% of all cases of thyroid cancer (TC). Aberrant activation of RET (rearranged during transfection) signaling via somatic mutations is the basic molecular mechanism of MTC tumorigenicity. In this study, we determined the incidence of R...

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Principais autores: Elham Shakiba, Mehdi Hedayati, Ahmad Majd, Monireh Movahedi
פורמט: Artigo
שפה:Inglês
יצא לאור: Zabol University of Medical sciences 2020-09-01
סדרה:International Journal of Basic Science in Medicine
נושאים:
ret gene
somatic mutations
iranian patient
medullary thyroid carcinoma
thyroid
caner
גישה מקוונת:http://ijbsm.zbmu.ac.ir/PDF/ijbsm-20430
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