Gene Expression in Transformed Lymphocytes Reveals Variation in Endomembrane and HLA Pathways Modifying Cystic Fibrosis Pulmonary Phenotypes

Variation in cystic fibrosis (CF) phenotypes, including lung disease severity, age of onset of persistent Pseudomonas aeruginosa (P. aeruginosa) lung infection, and presence of meconium ileus (MI), has been partially explained by genome-wide association studies (GWASs). It is not expected that GWASs...

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Publicado no:Am J Hum Genet
Main Authors: O’Neal, Wanda K., Gallins, Paul, Pace, Rhonda G., Dang, Hong, Wolf, Whitney E., Jones, Lisa C., Guo, XueLiang, Zhou, Yi-Hui, Madar, Vered, Huang, Jinyan, Liang, Liming, Moffatt, Miriam F., Cutting, Garry R., Drumm, Mitchell L., Rommens, Johanna M., Strug, Lisa J., Sun, Wei, Stonebraker, Jaclyn R., Wright, Fred A., Knowles, Michael R.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
Assuntos:
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4320265/
https://ncbi.nlm.nih.gov/pubmed/25640674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2014.12.022
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