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Bacterial Lipopolysaccharide Augments Febrile-Range Hyperthermia-Induced Heat Shock Protein 70 Expression and Extracellular Release in Human THP1 Cells

Sepsis, a devastating and often lethal complication of severe infection, is characterized by fever and dysregulated inflammation. While infections activate the inflammatory response in part through Toll-like receptors (TLRs), fever can partially activate the heat shock response with generation of he...

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Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Tulapurkar, Mohan E., Ramarathnam, Aparna, Hasday, Jeffrey D., Singh, Ishwar S.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4320107/
https://ncbi.nlm.nih.gov/pubmed/25659128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0118010
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