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Role of high-molecular-weight kininogen in surface-binding and activation of coagulation Factor XI and prekallikrein.

In the contact phase of activation of the kinin-forming, intrinsic clotting, and fibrinolytic systems, high-molecular-weight kininogen acts as a cofactor for the activation of Factor XI, prekallikrein, and Hageman factor. One mechanism by which high-molecular-weight kininogen acts as a cofactor has...

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Dettagli Bibliografici
Autori principali: Wiggins, R C, Bouma, B N, Cochrane, C G, Griffin, J H
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1977
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC432002/
https://ncbi.nlm.nih.gov/pubmed/270705
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