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Human leukocytic pyrogen: purification and development of a radioimmunoassay.

Leukocytic pyrogen is a small endogenous protein that mediates fever. Because of the limitations of bioassays, circulating leukocytic pyrogen has not been demonstrated during fever in humans. The pyrogen was produced in vitro after phagocytosis of staphylococci by blood monocytes. Antibody against t...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Dinarello, C A, Renfer, L, Wolff, S M
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1977
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC431999/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/22079/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.74.10.4624
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