Human leukocytic pyrogen induces release of specific granule contents from human neutrophils.

The ability of highly purified human leukocytic pyrogen (LP) to induce neutrophil lysosomal protein release is described. Human peripheral blood neutrophils isolated by Ficoll-Hypaque and dextran sedimentation were exposed to purified human LP. The specific granule-associated proteins, lysozyme and...

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Bibliographic Details
Published in:J Clin Invest
Main Authors: Klempner, M S, Dinarello, C A, Gallin, J I
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 1978
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Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC372655/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/659595/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI109050
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