SMAD-Independent Down-Regulation of Caveolin-1 by TGF-β: Effects on Proliferation and Survival of Myofibroblasts

Transforming growth factor-β (TGF-β) mediates growth-inhibitory effects on most target cells via activation of the canonical SMAD signaling pathway. This growth-inhibitory activity may be coupled with cellular differentiation. Our studies demonstrate that TGF-β1 inhibits proliferation of primary, no...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Sanders, Yan Y., Cui, Zongbin, Le Saux, Claude Jourdan, Horowitz, Jeffrey C., Rangarajan, Sunad, Kurundkar, Ashish, Antony, Veena B., Thannickal, Victor J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4319960/
https://ncbi.nlm.nih.gov/pubmed/25658089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0116995
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