Tritium suicide selection of mammalian cell mutants defective in the transport of neutral amino acids.

Mouse lymphocytic cells of the established line GF-14 were allowed to accumulate intracellular 3H-labeled aminoisobutyric acid (AIB), frozen, and stored over liquid N2. After internal radiation had reduced survival to 1 in 10(4), survivors were plated and tested for their ability to transport AIB. O...

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Main Authors: Finkelstein, M C, Slayman, C W, Adelberg, E A
Format: Artigo
Sprog:Inglês
Udgivet: 1977
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC431983/
https://ncbi.nlm.nih.gov/pubmed/200920
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