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Maternal-zygotic knockout reveals a critical role of Cdx2 in the morula to blastocyst transition

The first lineage segregation in the mouse embryo generates the inner cell mass (ICM), which gives rise to the pluripotent epiblast and therefore the future embryo, and the trophectoderm (TE), which will build the placenta. The TE lineage depends on the transcription factor Cdx2. However, when Cdx2...

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Bibliografiske detaljer
Udgivet i:Dev Biol
Main Authors: Jedrusik, Agnieszka, Cox, Andy, Wicher, Krzysztof, Glover, David M., Zernicka-Goetz, Magdalena
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4319684/
https://ncbi.nlm.nih.gov/pubmed/25512302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2014.12.004
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