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Maternal Argonaute 2 Is Essential for Early Mouse Development at the Maternal-Zygotic Transition

Activation of zygotic gene expression in the two-cell mouse embryo is associated with destruction of maternally inherited transcripts, an important process for embryogenesis about which little is understood. We asked whether the Argonaute (Ago)/RNA-induced silencing complex, providing the mRNA “slic...

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Autors principals: Lykke-Andersen, Karin, Gilchrist, Michael J., Grabarek, Joanna B., Das, Partha, Miska, Eric, Zernicka-Goetz, Magdalena
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2555945/
https://ncbi.nlm.nih.gov/pubmed/18701707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-02-0219
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