Choroid plexus dysfunction impairs beta-amyloid clearance in a triple transgenic mouse model of Alzheimer’s disease

Compromised secretory function of choroid plexus (CP) and defective cerebrospinal fluid (CSF) production, along with accumulation of beta-amyloid (Aβ) peptides at the blood-CSF barrier (BCSFB), contribute to complications of Alzheimer’s disease (AD). The AD triple transgenic mouse model (3xTg-AD) at...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Front Cell Neurosci
Huvudupphovsmän: González-Marrero, Ibrahim, Giménez-Llort, Lydia, Johanson, Conrad E., Carmona-Calero, Emilia María, Castañeyra-Ruiz, Leandro, Brito-Armas, José Miguel, Castañeyra-Perdomo, Agustín, Castro-Fuentes, Rafael
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2015
Ämnen:
Neuroscience
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4319477/
https://ncbi.nlm.nih.gov/pubmed/25705176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2015.00017
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk