Choroid plexus dysfunction impairs beta-amyloid clearance in a triple transgenic mouse model of Alzheimer’s disease

Compromised secretory function of choroid plexus (CP) and defective cerebrospinal fluid (CSF) production, along with accumulation of beta-amyloid (Aβ) peptides at the blood-CSF barrier (BCSFB), contribute to complications of Alzheimer’s disease (AD). The AD triple transgenic mouse model (3xTg-AD) at...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Front Cell Neurosci
Auteurs principaux: González-Marrero, Ibrahim, Giménez-Llort, Lydia, Johanson, Conrad E., Carmona-Calero, Emilia María, Castañeyra-Ruiz, Leandro, Brito-Armas, José Miguel, Castañeyra-Perdomo, Agustín, Castro-Fuentes, Rafael
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2015
Sujets:
Neuroscience
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4319477/
https://ncbi.nlm.nih.gov/pubmed/25705176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2015.00017
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires