Choroid plexus dysfunction impairs beta-amyloid clearance in a triple transgenic mouse model of Alzheimer’s disease

Compromised secretory function of choroid plexus (CP) and defective cerebrospinal fluid (CSF) production, along with accumulation of beta-amyloid (Aβ) peptides at the blood-CSF barrier (BCSFB), contribute to complications of Alzheimer’s disease (AD). The AD triple transgenic mouse model (3xTg-AD) at...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: González-Marrero, Ibrahim, Giménez-Llort, Lydia, Johanson, Conrad E., Carmona-Calero, Emilia María, Castañeyra-Ruiz, Leandro, Brito-Armas, José Miguel, Castañeyra-Perdomo, Agustín, Castro-Fuentes, Rafael
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4319477/
https://ncbi.nlm.nih.gov/pubmed/25705176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2015.00017
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