Differentiation of hypothalamic-like neurons from human pluripotent stem cells

The hypothalamus is the central regulator of systemic energy homeostasis, and its dysfunction can result in extreme body weight alterations. Insights into the complex cellular physiology of this region are critical to the understanding of obesity pathogenesis; however, human hypothalamic cells are l...

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Vydáno v:J Clin Invest
Hlavní autoři: Wang, Liheng, Meece, Kana, Williams, Damian J., Lo, Kinyui Alice, Zimmer, Matthew, Heinrich, Garrett, Martin Carli, Jayne, Leduc, Charles A., Sun, Lei, Zeltser, Lori M., Freeby, Matthew, Goland, Robin, Tsang, Stephen H., Wardlaw, Sharon L., Egli, Dieter, Leibel, Rudolph L.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2015
Témata:
Technical Advance
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4319421/
https://ncbi.nlm.nih.gov/pubmed/25555215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI79220
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