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GP96 is a GARP chaperone and controls regulatory T cell functions
Molecular chaperones control a multitude of cellular functions via folding chaperone-specific client proteins. CD4(+)FOXP3(+) Tregs play key roles in maintaining peripheral tolerance, which is subject to regulation by multiple molecular switches, including mTOR and hypoxia-inducible factor. It is no...
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| 發表在: | J Clin Invest |
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| Main Authors: | , , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Clinical Investigation
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4319419/ https://ncbi.nlm.nih.gov/pubmed/25607841 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI79014 |
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