GP96 is a GARP chaperone and controls regulatory T cell functions

Molecular chaperones control a multitude of cellular functions via folding chaperone-specific client proteins. CD4(+)FOXP3(+) Tregs play key roles in maintaining peripheral tolerance, which is subject to regulation by multiple molecular switches, including mTOR and hypoxia-inducible factor. It is no...

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Bibliografiska uppgifter
I publikationen:J Clin Invest
Huvudupphovsmän: Zhang, Yongliang, Wu, Bill X., Metelli, Alessandra, Thaxton, Jessica E., Hong, Feng, Rachidi, Saleh, Ansa-Addo, Ephraim, Sun, Shaoli, Vasu, Chenthamarakshan, Yang, Yi, Liu, Bei, Li, Zihai
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Clinical Investigation 2015
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4319419/
https://ncbi.nlm.nih.gov/pubmed/25607841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI79014
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