Analysis of the T-cell receptor beta-chain variable-region (V beta) repertoire in monozygotic twins discordant for human immunodeficiency virus: evidence for perturbations of specific V beta segments in CD4+ T cells of the virus-positive twins.

We analyzed the T-cell receptor (TCR) V beta repertoire in human immunodeficiency virus type 1 (HIV-1)-infected individuals at different stages of disease. To circumvent the effect of HLA and other loci on the expressed TCR repertoire, we compared the TCR repertoire in nine pairs of monozygotic twin...

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Bibliografiske detaljer

Udgivet i:	Proc Natl Acad Sci U S A
Principais autores:	Rebai, N, Pantaleo, G, Demarest, J F, Ciurli, C, Soudeyns, H, Adelsberger, J W, Vaccarezza, M, Walker, R E, Sekaly, R P, Fauci, A S
Format:	Artigo
Sprog:	Inglês
Udgivet:	National Academy of Sciences 1994
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC43193/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7906416/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.4.1529
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