Analysis of the T-cell receptor beta-chain variable-region (V beta) repertoire in monozygotic twins discordant for human immunodeficiency virus: evidence for perturbations of specific V beta segments in CD4+ T cells of the virus-positive twins.

We analyzed the T-cell receptor (TCR) V beta repertoire in human immunodeficiency virus type 1 (HIV-1)-infected individuals at different stages of disease. To circumvent the effect of HLA and other loci on the expressed TCR repertoire, we compared the TCR repertoire in nine pairs of monozygotic twin...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Rebai, N, Pantaleo, G, Demarest, J F, Ciurli, C, Soudeyns, H, Adelsberger, J W, Vaccarezza, M, Walker, R E, Sekaly, R P, Fauci, A S
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1994
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC43193/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7906416/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.4.1529
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