Analysis of the T-cell receptor beta-chain variable-region (V beta) repertoire in monozygotic twins discordant for human immunodeficiency virus: evidence for perturbations of specific V beta segments in CD4+ T cells of the virus-positive twins.

We analyzed the T-cell receptor (TCR) V beta repertoire in human immunodeficiency virus type 1 (HIV-1)-infected individuals at different stages of disease. To circumvent the effect of HLA and other loci on the expressed TCR repertoire, we compared the TCR repertoire in nine pairs of monozygotic twin...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Rebai, N, Pantaleo, G, Demarest, J F, Ciurli, C, Soudeyns, H, Adelsberger, J W, Vaccarezza, M, Walker, R E, Sekaly, R P, Fauci, A S
Format: Artigo
Langue:Inglês
Publié: 1994
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC43193/
https://ncbi.nlm.nih.gov/pubmed/7906416
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