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Macitentan: An important addition to the treatment of pulmonary arterial hypertension

Macitentan is an orphan drug for the treatment of pulmonary arterial hypertension (PAH). Endothelin-1 (ET-1) plays a critical role of pathophysiology of PAH. Macitentan, a new dual endothelin receptor antagonist, has reportedly improved prognosis of PAH patients by delaying the progression of diseas...

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Detaylı Bibliyografya
Yayımlandı:J Pharmacol Pharmacother
Asıl Yazarlar: Khadka, Anjan, Singh Brashier, Dick B, Tejus, Anantharamu, Sharma, Ashok Kumar
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Medknow Publications & Media Pvt Ltd 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4319253/
https://ncbi.nlm.nih.gov/pubmed/25709357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0976-500X.149151
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