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Macitentan: An important addition to the treatment of pulmonary arterial hypertension
Macitentan is an orphan drug for the treatment of pulmonary arterial hypertension (PAH). Endothelin-1 (ET-1) plays a critical role of pathophysiology of PAH. Macitentan, a new dual endothelin receptor antagonist, has reportedly improved prognosis of PAH patients by delaying the progression of diseas...
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| Publicado no: | J Pharmacol Pharmacother |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Medknow Publications & Media Pvt Ltd
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4319253/ https://ncbi.nlm.nih.gov/pubmed/25709357 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0976-500X.149151 |
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