Nonspecific DNA binding of genome-regulating proteins as a biological control mechanism: Measurement of DNA-bound Escherichia coli lac repressor in vivo

Binding of genome regulatory proteins to nonspecific DNA sites may play an important role in controlling the thermodynamics and kinetics of the interactions of these proteins with their specific target DNA sequences. An estimate of the fraction of Escherichia coli lac repressor molecules bound in vi...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Kao-Huang, Ying, Revzin, Arnold, Butler, Andrew P., O'Conner, Pamela, Noble, Daniel W., Von Hippel, Peter H.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1977
Assuntos:	Biological Sciences: Biochemistry
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC431912/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/412185/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.74.10.4228
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