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Nonspecific DNA binding of genome-regulating proteins as a biological control mechanism: Measurement of DNA-bound Escherichia coli lac repressor in vivo

Binding of genome regulatory proteins to nonspecific DNA sites may play an important role in controlling the thermodynamics and kinetics of the interactions of these proteins with their specific target DNA sequences. An estimate of the fraction of Escherichia coli lac repressor molecules bound in vi...

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Bibliografiske detaljer
Main Authors: Kao-Huang, Ying, Revzin, Arnold, Butler, Andrew P., O'Conner, Pamela, Noble, Daniel W., Von Hippel, Peter H.
Format: Artigo
Sprog:Inglês
Udgivet: 1977
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC431912/
https://ncbi.nlm.nih.gov/pubmed/412185
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