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Crystal Structure of Subunits D and F in Complex Gives Insight into Energy Transmission of the Eukaryotic V-ATPase from Saccharomyces cerevisiae

Eukaryotic V(1)V(O)-ATPases hydrolyze ATP in the V(1) domain coupled to ion pumping in V(O). A unique mode of regulation of V-ATPases is the reversible disassembly of V(1) and V(O), which reduces ATPase activity and causes silencing of ion conduction. The subunits D and F are proposed to be key in t...

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Balakrishna, Asha Manikkoth, Basak, Sandip, Manimekalai, Malathy Sony Subramanian, Grüber, Gerhard
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4318993/
https://ncbi.nlm.nih.gov/pubmed/25505269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.622688
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