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Type V OI Primary Osteoblasts Display Increased Mineralization Despite Decreased COL1A1 Expression
CONTEXT: Patients with type V osteogenesis imperfecta (OI) are heterozygous for a dominant IFITM5 c.-14C>T mutation, which adds five residues to the N terminus of bone-restricted interferon-induced transmembrane-like protein (BRIL), a transmembrane protein expressed in osteoblasts. Type V OI skel...
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| Publicado no: | J Clin Endocrinol Metab |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Endocrine Society
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4318905/ https://ncbi.nlm.nih.gov/pubmed/25387264 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2014-3082 |
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