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Evidence for a long-range conformational change induced by antigen binding to IgM antibody.

The effects of antigen binding on IgM antibody conformation were investigated by measuring the immunological reactivity of the Fc-bound J polypeptide. For such measurements anti-azophenyl-beta-D-lactoside and anti-azobenzenearsonate IgM antibodies were examined in a J chain radioimmunoassay before a...

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Bibliografiske detaljer
Main Authors: Brown, J C, Koshland, M E
Format: Artigo
Sprog:Inglês
Udgivet: 1977
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC431857/
https://ncbi.nlm.nih.gov/pubmed/74832
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