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Transglutaminase 2 Promotes PDGF-Mediated Activation of PDGFR/Akt1 and β-catenin Signaling in Vascular Smooth Muscle Cells and Supports Neointima Formation

BACKGROUND: Phenotypic switch of vascular smooth muscle cells (VSMCs) accompanies neointima formation and associates with vascular diseases. Platelet derived growth factor (PDGF)-induced activation of PDGFR/Akt1 and β-catenin signaling pathways in VSMCs has been implicated in vessel occlusion. Trans...

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Bibliografske podrobnosti
izdano v:J Vasc Res
Main Authors: Nurminskaya, Maria, Beazley, Kelly E., Smith, Elizabeth P., Belkin, Alexey M.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4318569/
https://ncbi.nlm.nih.gov/pubmed/25612735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000369461
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