IMPLICATION FOR TRANSGLUTAMINASE 2-MEDIATED ACTIVATION OF β-CATENIN SIGNALING IN NEOINTIMAL VASCULAR SMOOTH MUSCLE CELLS IN CHRONIC CARDIAC ALLOGRAFT REJECTION

BACKGROUND: Cardiac allograft vasculopathy (CAV) remains the main cause of long-term transplant rejection. It is characterized by hyperproliferation of vascular smooth muscle cells (VSMCs). Canonical β-catenin signaling is a critical regulator of VSMC proliferation in development; however, the role...

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Detalhes bibliográficos
Main Authors: Beazley, K.E., Zhang, T., Lima, F., Pozharskaya, T., Niger, C., Tsitsikov, E., Azimzadeh, A.M., Nurminskaya, M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3509739/
https://ncbi.nlm.nih.gov/pubmed/22694852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.healun.2012.04.009
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