Caveolin-1 accumulation in the tongue cancer tumor microenvironment is significantly associated with poor prognosis: an in-vivo and in-vitro study

BACKGROUND: Caveolin-1 (CAV1) may be upregulated by hypoxia and acts in a tumor-dependent manner. We investigated CAV1 in tongue squamous cell carcinoma (TSCC) and its association with clinical outcomes, and studied in vitro possible ways for CAV1 accumulation in the tumor microenvironment (TME). ME...

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Bibliografiska uppgifter
I publikationen:BMC Cancer
Huvudupphovsmän: Vered, Marilena, Lehtonen, Meri, Hotakainen, Lari, Pirilä, Emma, Teppo, Susanna, Nyberg, Pia, Sormunen, Raija, Zlotogorski-Hurvitz, Ayelet, Salo, Tuula, Dayan, Dan
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2015
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4318139/
https://ncbi.nlm.nih.gov/pubmed/25633184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1030-6
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