Caveolin-1 accumulation in the tongue cancer tumor microenvironment is significantly associated with poor prognosis: an in-vivo and in-vitro study

BACKGROUND: Caveolin-1 (CAV1) may be upregulated by hypoxia and acts in a tumor-dependent manner. We investigated CAV1 in tongue squamous cell carcinoma (TSCC) and its association with clinical outcomes, and studied in vitro possible ways for CAV1 accumulation in the tumor microenvironment (TME). ME...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Vered, Marilena, Lehtonen, Meri, Hotakainen, Lari, Pirilä, Emma, Teppo, Susanna, Nyberg, Pia, Sormunen, Raija, Zlotogorski-Hurvitz, Ayelet, Salo, Tuula, Dayan, Dan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4318139/
https://ncbi.nlm.nih.gov/pubmed/25633184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1030-6
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